Andy Murray, a former world number one, had accepted a wild-card entry last year but didn't go after testing positive for COVID-19 shortly before he was due to board a charter flight to Melbourne.
It was Andy Murray's second victory over a top-10 opponent in the past two weeks. He will next face Tommy Paul.
Andy Murray saved a set point before closing it out on his third match point in the Stockholm Open.
The victory marks Marin Cilic's fourth title in Russia after two wins in 2014 and 2015 in Moscow.
This is the first loss for British tennis player Andy Murray in 10 matches at the Austrian indoor event.
The 34-year-old 3-time Grand Slam Champion will face Casper Rudd of Norway in the round of 16.
The contest stretched to almost five hours and Murray didn't appreciate Tsitsipas taking a medical timeout after the third set and a lengthy visit to the locker room after the fourth
Murray lost to much younger Tsitsipas 2-6, 7-6 (7), 3-6, 6-3, 6-4, as the year's last Grand Slam tournament got underway
Murray now heads to the US Open, where he won the first of his three Grand Slam titles in 2012
Murray's ranking slid out of the top 100 after he had two hip operations in recent years
Andy Murray remained in the doubles tournament with partner Joe Salisbury. Murray and Salisbury beat the second-seeded French team of Pierre-Hughes Herbert and Nicolas Mahut 6-3, 6-2 on Saturday
Denis Shapovalov defeated Andy Murray,a two-time champion at Wimbledon, 6-4, 6-2, 6-2,
After wasting a pair of match points and ceding the third set, Murray defeated Basilashvili 6-4, 6-3, 5-7, 6-3
Andy Murray is making a return, while Coco Gauff hopes to make an impression again even as Wimbledon rings in a host of changes
A five-time champion of this event, Murray was a wild-card entry. He will play at Wimbledon in less than two weeks as a wild card.
The Gentlemen's and Ladies' singles winners at Wimbledon will each get USD 2.4 million, a nearly 28 percent decrease from the 2019 edition
Andy Murray will miss the French Open as he focuses on being ready for playing on grass at Queen's Club and Wimbledon
Former world number one Andy Murray will compete at the Miami Open for the first time since 2016 after being granted a wildcard.
A farmer sits near his red chillies at a deserted APMC market, during the weekend curfew imposed by the Karnataka government to curb the spread of COVID-19, in Hubballi.PTI Photo
Delhi Chief Minister & AAP National Convenor Arvind Kejriwal being welcomed by women supporters during his door-to-door campaign ahead of the Goa Assembly elections, in Goa.PTI Photo
A health worker collects swab sample of a woman for COVID-19 test, amid concerns over rising Omicron cases, in Gurugram.PTI Photo
Traffic jam on a road at Shalimar Bagh during the weekend curfew imposed by the Delhi government to curb the spread of Covid-19, in New Delhi.PTI Photo/ Shahbaz Khan
The Lajpat Nagar market wears a deserted look during the weekend curfew imposed by the Delhi government to curb the spread of Covid-19, in New Delhi.PTI Photo/ Shahbaz Khan
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