Advertisement
Wednesday, Oct 05, 2022
Outlook.com
Outlook.com

Covaxin And Covishield Taken In Mix And Match, 4 Times Effective: Study

If Covishield and Covaxin are taken as first and second shots in any order, the antibody response becomes 4 times higher, a study by Hyderabad-based AIG Hospitals said.

Covaxin And Covishield Taken In Mix And Match, 4 Times Effective: Study
Representational Image | Twitter
Covaxin And Covishield Taken In Mix And Match, 4 Times Effective: Study
outlookindia.com
2022-01-04T11:42:50+05:30

Mixing of Covid-19 vaccines Covaxin and Covishield as first and second doses or vice versa was found to be four times effective, a study by Hyderabad-based AIG Hospitals along with a team of researchers from the Asian Healthcare Foundation has said.

The study was conducted to determine the safety profile of mixing Covishied and Covaxin along with checking the antibody response, a press release from AIG said on Monday.
The most important finding of the study was that the Spike-protein neutralizing antibodies found in the mixed vaccine groups were significantly higher than the same-vaccine groups, D Nageshwar Reddy, Chairman of AIG Hospitals said.

“Spike-protein neutralizing antibodies are the ones which kill the virus and reduce the overall infectivity. We found that when the first and second dose are of different vaccines, the Spike-protein antibody response is four times higher compared to two-dose of same vaccine,” Dr. Reddy who is also among the researchers involved in the study said.

The findings are particularly important when considering administering third booster dose aiming to elicit robust antibody response and help in killing the virus, he said.
Mixed doses can certainly boost these Spike-protein neutralizing antibodies and will enhance the vaccines’ effectiveness even against the Omicron variant, Reddy added.

The study results show that mixing of Covid-19 Vaccines (Covishield and Covaxin) provide higher antibody response and is safe as well. Furthermore, AIG Hospitals has shared the data fromthe study with the ICMR (Indian Council for Medical Research) to be considered as a reference study while deciding on the “Prevention” doses starting January 10.

A total of 330 healthy volunteers who were not vaccinated and had no history of Covid-19 infection were selected and screened for SARS-CoV-2 antibodies for the study. Out of 330, 44 participants were found to be seronegative, as they didn’t have Covid-19 related antibodies.

“One of the incidental findings of the study is the seropositivity among the population. Eighty seven per cent participants who didn’t get vaccinated and never tested positive for Covid had the Covid-19 related antibodies. This means our population might have developed significant antibodies against the Covid because of the huge Delta wave that we endured,” Dr.Reddy said.

The third Covid-wave led by the Omicron variant has started in India. Although the initial data indicates that this wave will be milder than the previous Delta one with less hospitalization, still a large section of the population might get affected, the release said.

Advertisement

Outlook Newsletters

Advertisement
Advertisement
Advertisement

Read More from Outlook

Lament Of Separation: Songs Of Habba Khatun, Last Queen Of Kashmir, Still Echo In Valley

Lament Of Separation: Songs Of Habba Khatun, Last Queen Of Kashmir, Still Echo In Valley

In happy times and sad, Habba Khatun’s sensuous songs make both young and old emotional. With the never-ending conflict bringing tragedies to every doorstep, Habba’s lyrics of separation amplify their mourning.

How Indian Laws Govern People’s Right To Love And Live

How Indian Laws Govern People’s Right To Love And Live

In India, only those relationships between a man and a woman are considered to be legitimate when there is a marriage between the two.

Kohli Quits Test Captaincy, Leaves Leadership Vacuum

Kohli Quits Test Captaincy, Leaves Leadership Vacuum

Virat Kohli, 33, had recently stepped down as India's T20I captain and was subsequently removed as the ODI captain.

UP Elections 2022: How Congress Is Harnessing Power Of 'Persecuted' Women To Counter BJP

UP Elections 2022: How Congress Is Harnessing Power Of 'Persecuted' Women To Counter BJP

A Mahila Congress leader, who is the face of the ‘Ladki Hoon, Lad Sakti Hoon’ campaign, however, has accused the party of anti-women bias after she was denied a ticket.

Advertisement